Devour follows the story of "The Virginia Bitches," an all-female death metal band who are vampires by night and on the verge of stardom. After they save a young girl in the road who is on the run from a mysterious cult they become trapped in small town full of cannibals and led by a warlock. As the band members try to survive the night they must face not only grotesque horrors of a cannibal cult but also the dark supernatural forces that threaten to consume them all.